Pregnancy
Conditions
Keywords
Vitamin B12 absorption, Pregnancy
Brief summary
During pregnancy the woman uses more vitamin B12, but we do not know, whether it is through increased absorption or it eats into the womans vitamin B12 deposit . Sufficient B-vitamin is crucial for the normal development af foetus during pregnancy. In Denmark the National Board of Health recommend an intake of Folic Acid, from the day the woman wishes to be pregnant and to the 12. week of gestation, but there is no recommendation for vitamin B12. We will measure the vitamin B12 absorption with a new non-radioactive test, CobaSorb. .
Interventions
DIETARY_SUPPLEMENTB12 vitamin (Cyanocobalamin)
Arm A: B12 vitamin (Cyanocobalamin)
Sponsors
University of Aarhus
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* the 13 week of gestation +/- 1 week (only fore pregnant women) * Between 20- 40 years * Northern European * abel to read and understand danish
Exclusion criteria
* treatment with vitamin B12 within the last 5 years * daily intake of vitamins that contain more than 1µg vitamin B12 * infectious disease * systemic disease * daily use of medicine that interferes with vitamin B12
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in vitamin B12 absorption during pregnancy, measured with CobaSorb. | 9 month |
Countries
Denmark
Outcome results
None listed