Preparation Rich in Growth Factors (PRGF) Treatment for Osteoarthritis of the Knee

PRP as a Treatment for Knee Osteoarthritis - Randomized-double-blind-placebo Control Trail.

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00728611

Enrollment

Registered

2008-08-06

Start date

2008-01-31

Completion date

2009-03-31

Last updated

2011-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the Knee

Brief summary

to evaluate the influence of PRGF treatment on patient suffering from OA knee

Detailed description

Autologous platelet-secreted growth factors (GFs) may have therapeutic effects in osteoarthritis (OA) capsular joints via multiple mechanisms. Our aim is to examine the effect of a platelet-derived preparation rich in growth factors (PRGFs) in OA knee

Interventions

BIOLOGICALPRGF

intra auricular injection 6mg

DRUGhyaluronic acid

20 mg / 2 ml

DRUGplacebo

physiological water 3cc + lidocain 3cc

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

40 Years to 75 Years

Healthy volunteers

Inclusion criteria

* age 40-75 years old * diagnosed Oa of the knee more then 1 year * no knee deformation

Exclusion criteria

* mental of physical disabilities * pregnancy * deformities of the knee

Design outcomes

Primary

Measure	Time frame
Improvment of symptomes	1 year

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026