Magnetic Resonance Imaging (MRI) of the Chest
Conditions
Keywords
participants, scheduled, clinically, ordered, MRI
Brief summary
The purpose of the study is to improve chest MRI exams, eventually resulting in improvements in patient care.
Detailed description
We will recruit patients to participate in the assessment of new MRI technologies designed to improve chest MRI exams that will result in improvements in patient care. Several different MRI technologies will be evaluated. Specific evaluation of distinct technologies (eg. new head coil design, and new imaging sequence for the spine) may be evaluated simultaneously, or over non-overlapping periods in time.
Interventions
PROCEDUREMRI -Clinical
MRI done is standard of care
PROCEDUREMRI-Research
MRI includes extra sequences
Sponsors
University of Michigan
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* If you are a male or a non-pregnant female patient, age 18 years or older, of any ethnic background presenting to MRI for a clinically-ordered chest MRI exam, you are eligible to participate in this study. * If you are a female of child bearing potential you will be questioned for the possibility of pregnancy. Pregnancy screening, if necessary, is performed routinely by ordering physicians prior to MRI scanning to confirm the patient is not pregnant.
Exclusion criteria
* Patients who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator. * Pregnant patients or patients who are nursing * Patients who are claustrophobic.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| New MRI Technologies | 3 years | Assessment of the new technologies will be quantified by a variety of performance and image quality/content measures. The appropriate set of measures will be selected based on specific features offered by each assessed technology, but will be drawn from the following quantities: 1. Scan speed: Scan speed is time required to set-up and run the new technique relative to the standard method. 2. Signal to noise: SNR (signal to noise ratio)is the ratio of average image intensity in target tissue relative to standard deviation of background areas (outside of body). This is a fundamental parameter used to quantify relative performance of new imaging sequences/hardware/software. 3. Contrast to noise: CNR (contrast to noise)is the difference in average image intensity between two target tissues relative to noise. This is a key descriptor to quantity lesion/tissue conspicuity, thus is used to characterize relative performance of new imaging sequence/hardware/software. |
Countries
United States
Outcome results
None listed