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Chronic Pain and Opioid Dependence Assessment and Treatment

Chronic Pain and Opioid Dependence Assessment and Treatment

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00727675
Acronym
CPODAT
Enrollment
15
Registered
2008-08-04
Start date
2008-08-31
Completion date
2015-07-31
Last updated
2020-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Pain, Opioid Dependency

Keywords

chronic pain, opioid dependence, Cognitive Behavioral Therapy (CBT)

Brief summary

This study involves the development of an integrated psychotherapy that addresses both chronic pain and opioid dependence(POD).

Detailed description

To conduct a pre-pilot study with 20 POD patients to a) evaluate the acceptability and potential efficacy of specific sessions (i.e., reduced illicit opioid use as assessed by urine toxicology and self-report findings, and decreased pain as evidenced by attenuated pain intensity and pain interference on self-report measures from baseline throughout treatment) for inclusion in integrated Cognitive Behavioral Therapy (CBT) for POD and the sequence of sessions, b) assess patients' satisfaction with integrated CBT as evidenced by qualitative feedback from individual exit interviews, and c) develop and modify initial therapist training and process rating measures. Products will include a) a manual for integrated CBT for POD to be used in opioid treatment programs and primary care settings with POD patients, b) therapist training materials, and c) process rating instruments.

Interventions

CBT is provided by skilled psychologists in weekly sessions for 12 weeks and focuses on reducing illicit drug use and increasing pain management.

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
Yale University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* at least 18 years of age * currently in Methadone Maintenance Treatment (MMT) at the APT Foundation in New Haven, CT * opioid dependence * experience moderate to severe chronic pain

Exclusion criteria

* current suicide or homicide risk * are unable to complete the informed consent or surveys because of psychiatric impairment * have cognitive impairment * are unable to read or understand English

Design outcomes

Primary

MeasureTime frame
Reduced illicit opioid use and pain12 weeks

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 1, 2026