Effect of Rifampin on Bosutinib When Both Are Given to Healthy People

A Study to Examine the Potential Effect of Rifampin on the Pharmacokinetics of Bosutinib When Administered Concomitantly to Healthy Subjects

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00725426

Enrollment

Registered

2008-07-30

Start date

2008-07-31

Completion date

2008-08-31

Last updated

2009-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

healthy subjects

Brief summary

Study to examine whether rifampin has an effect on the pharmacokinetics of bosutinib.

Interventions

DRUGBosutinib

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy men age 18-50 * Healthy women of nonchildbearing potential, age 18-50

Design outcomes

Primary

Measure	Time frame
Pharmacokinetics (plasma concentrations)	4 weeks

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026