Comparison of OPTI-FREE RepleniSH and ReNu Multi-Plus Lens Care Regimens on Corneal Epithelium

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00724269

Enrollment

Registered

2008-07-29

Start date

2009-10-31

Completion date

2011-07-31

Last updated

2012-10-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contact Lens Wear

Keywords

Contact lens wear, multi-purpose solution, corneal staining

Brief summary

The purpose of this study is to evaluate the corneal epithelium after soft contact lens wear and use of two marketed multi-purpose solutions.

Interventions

DEVICEOPTI-FREE RepleniSH

Multi-Purpose Solution for soft contact lenses

DEVICEReNu MultiPlus MPS

Multi-Purpose Solution for soft contact lenses

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SCREENING

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Successful contact lens wear on a daily wear basis * Wear contact lenses at least 8 hours/day * Vision correctable to at least 20/30 * Normal Eyes * Other protocol-defined inclusion criteria may apply Exclusion: * Topical ocular medication use * Other protocol-defined inclusion criteria may apply

Design outcomes

Primary

Measure	Time frame
Confocal microscopy analysis of Corneal Epithelium	2 weeks

Secondary

Measure	Time frame
Patient comfort	2 weeks
Corneal Staining	2 weeks

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026