Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

Status

Completed

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00721643

Enrollment

Registered

2008-07-24

Start date

2008-07-31

Completion date

2010-12-31

Last updated

2017-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oxidative Stress

Keywords

Angelica keiskei, absorption kinetics, quercetin

Brief summary

The absorption kinetics of polyphenols in angel's plant (Angelica keiskei), which is a dark green leafy vegetable rich in antioxidant nutrients, will be determined in older adults in this pilot study.

Interventions

DIETARY_SUPPLEMENTangel's plant (Angelica keiskei)

Healthy control, one time dose of 5g dry power of Angelica keiskei

DIETARY_SUPPLEMENTAngel's plant (Angelica keiskei)

Metaboic syndrome subjects, one time dose of 5g dry powder of angel's plant (Angelica keiskei)

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Healthy subjects (\>60 yr, n=5) * subjects with metabolic syndrome (\>60 yr, n=5) * Subjects who has * high fasting plasma glucose (\>5.6 mmol/L), * central obesity (waist-hip ratio, \>0.9 for men, \>0.85 for women) * either high blood pressure (\>130/85 mmHg) or high triacylglycerol (\>1.7 mmol/L) will be selected to have metabolic syndrome. * normal hematological parameters, normal serum albumin, normal liver function, and normal kidney function * no history of smoking or alcoholism.

Exclusion criteria

* consume \>7 alcoholic drinks/wk * taking cholesterol medication or hormone replacement

Design outcomes

Primary

Measure	Time frame
Plasma quercetin	0, 30, 60, 100, 180, 240, 300, 360, 420 & 480 min

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026