Can Ultrasound Replace Amniocentesis for Confirming Fetal Lung Maturation Among Premature Fetuses?

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00720252

Enrollment

Registered

2008-07-22

Start date

2008-07-31

Completion date

2013-12-31

Last updated

2015-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal Lung Maturity

Brief summary

The purpose of this study is to measure prenatally with ultrasound the intratracheal flow volume displaced during breathing cycle in premature fetuses and to check whether a relationship exists between the inspired fluid and fetal lung maturation.

Interventions

DEVICEUltrasound

To measure intratracheal flow volume (and peak velocity) displaced during breathing cycle in premature fetuses.

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 48 Years

Healthy volunteers

Inclusion criteria

* Women delivering between 27 to 37 weeks. * Women undergoing amniocentesis for determining fetal lung maturity between 27 to 37 weeks.

Exclusion criteria

* Major fetal malformation. * Oligohydramnios or rupture of membranes diagnosed before 24 weeks of gestation.

Design outcomes

Primary

Measure	Time frame
To check whether a threshold exists between peak velocity and/or volume of fluid inspired by the fetus and lung maturation.	end of the study

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026