Assessment of the Effect of Food on ABT-143 Bioavailability

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00719693

Enrollment

115

Registered

2008-07-22

Start date

2008-07-31

Completion date

Unknown

Last updated

2012-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pharmacokinetic Variables

Keywords

Food effect, phase I, adverse events

Brief summary

Single-dose, open-label, two-period crossover study of ABT-143

Interventions

DRUGABT-143 ( rosuvastatin calcium and fenofibric acid )

one dose under low-fat meal condition

DRUGABT-143 (rosuvastatin calcium and fenofibric acid )

one dose under fasting meal condition

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

* 18-55 years of age (inclusive) * BMI 19 to 29 inclusive

Exclusion criteria

* Asian ancestry * Concurrent participation in another study * Females pregnant or breastfeeding

Design outcomes

Primary

Measure	Time frame
Pharmacokinetics	7 days

Secondary

Measure	Time frame
Adverse Events	30 days

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026