German Off Pump Coronary Artery Bypass in Elderly Study

Conditions

Heart Disease

Keywords

OPCAB, coronary, bypass, grafting, off pump

Brief summary

Comparison of two operative techniques (on-pump vs off-pump)of coronary revascularisation of the best treatment concept for patients older or 75 years old. Hypothesis: The coronary bypass operation without use of the heart-lung machine (off-pump=OPCAB) reduces the combined endpoint in comparison with the conventional coronary bypass operation (on-pump).

Anno Diegeler, Jochen Börgermann, Utz Kappert, Michael Hilker, Torsten Doenst et al. (15 authors)

Circulation2019-02-08101 citations

10.1161/circulationaha.118.035857

Female sex is not a risk factor for post procedural mortality in coronary bypass surgery in the elderly: A secondary analysis of the GOPCABE trial

Gloria Faerber, Michael Zacher, Wilko Reents, J. Boergermann, Utz Kappert et al. (9 authors)

PLoS ONE2017-08-3029 citations

10.1371/journal.pone.0184038

Off-pump versus on-pump coronary-artery bypass grafting in elderly patients.

Diegeler A, Börgermann J, Kappert U, Breuer M, Böning A, Ursulescu A, Rastan A, Holzhey D, Treede H, Rieß FC, Veeckmann P, Asfoor A, Reents W, Zacher M, Hilker M, GOPCABE Study Group.

2013-03-11314 citations

10.1056/nejmoa1211666

Interventions

OTHERcoronary artery bypass grafting

on pump off pump

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* older or 75 years * indication for elective bypass operation * patient has signed written consent before randomization

Exclusion criteria

* previous heart surgery * patient unable to give informed consent

Design outcomes

Primary

Measure	Time frame
renal failure	1 month and 12 month
Myocardial infarction	1 month and 12 month
Stroke	1 month and 12 month
Any revascularisation	1 month and30 month
All cause mortality	1 month and 12 month

Secondary

Measure	Time frame
blood transfusion	post op
length of stay in intensive-care unit	post op
ventilation time	post op

Countries

Germany

Outcome results

None listed