Neurophysiological Characterization of Postherniotomy Pain

Quantitative Sensory Testing in Persistent Postherniotomy Pain Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00719368

Enrollment

Registered

2008-07-21

Start date

2006-01-31

Completion date

2012-09-30

Last updated

2014-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathic Pain, Postherniotomy Pain, Postoperative Pain

Keywords

Groin hernia, pain, chronic, quantitative sensory testing, Persistent postoperative pain

Brief summary

Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome. By performing quantitative sensory testing, the specific changes in pain patients will be revealed, thereby aiding in designing future treatment trials. MRI scans of the groin regions in pain patients and control patients will be evaluated by senior MRI specialists assessing potential pathology to the region (Mesh, inflammation, edema, funicle etc.) Assessors will be blinded to clinical status, and surgery.

Interventions

None listed

Study design

Observational model

COHORT

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Male patients \>18 yrs * Inguinal herniotomy \>1 yr previously * No sign of hernia recurrence * Unilateral chronic groin pain lasting more than 3 months * Moderate/severe pain related impairment of everyday activities.

Exclusion criteria

* Other causes of persistent pain in groin region (hip, other surgical procedures)

Design outcomes

Primary

Measure	Time frame
Sensory function	actual

Countries

Denmark

Outcome results