Outcome of Embryo Culture at Two Oxygen Tensions

Does Reduced Oxygen Tension in Embryo Culture Influence Clinical Outcome of ICSI Cycles? A Prospective Randomized Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00718822

Enrollment

647

Registered

2008-07-21

Start date

2006-08-31

Completion date

2007-09-30

Last updated

2008-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Embryo Development

Keywords

clinical outcome, ICSI cycles, low oxygen, poor responders, pregnancy rate, prospective randomized study

Brief summary

The purpose of this study is to assess whether reduced oxygen tension in embryo culture has any effect on clinical outcome.

Interventions

OTHERoxygen concentration in the culture atmosphere

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

22 Years to 44 Years

Healthy volunteers

Inclusion criteria

* stimulated Intra Cytoplasmic Sperm Injection (ICSI) cycle

Exclusion criteria

* less than one mature (metaphase II) oocyte at the time of denudation

Design outcomes

Primary

Measure	Time frame
Ongoing pregnancy rate per cycle	10-11 weeks after embryo transfer

Secondary

Measure	Time frame
clinical pregnancy rate, implantation rate, early pregnancy loss, fertilization rate, embryo quality	—

Countries

Slovenia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026