Airway Secretion Clearance
Conditions
Keywords
Mucus Clearance, Secretion Clearance, HFCWO
Brief summary
To compare the outcomes of patients treated with the Vest and conventional chest physiotherapy to determine if the Vest provides equivalent therapy
Interventions
DEVICEAirway clearance Device
Provided by the Vest Airway clearance system
Sponsors
Hill-Rom
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Acute or chronic disease requiring secretion mobilization as per hospital protocol
Exclusion criteria
* Absolute contraindications for positional changes * Absolute contraindications for chest percussion * Women visibly pregnant * Previous enrollment in study * Previous CPT or Vest treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hospital Length of Stay | Admission to Discharge | an average of 10 days |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| HFCWO Arm Airway clearance provided by the Vest Airway Clearance System | 46 |
| CPT Arm Airway clearance provided by manual CPT | 59 |
| Total | 105 |
Baseline characteristics
| Characteristic | HFCWO Arm | CPT Arm | Total |
|---|---|---|---|
| Age, Continuous | 42 years STANDARD_DEVIATION 18 | 45 years STANDARD_DEVIATION 18 | 44 years STANDARD_DEVIATION 18 |
| Sex: Female, Male Female | 17 Participants | 33 Participants | 50 Participants |
| Sex: Female, Male Male | 29 Participants | 26 Participants | 55 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | — / — | — / — |
| other Total, other adverse events | 0 / 46 | 0 / 59 |
| serious Total, serious adverse events | 0 / 46 | 0 / 59 |
Outcome results
Primary
Hospital Length of Stay
an average of 10 days
Time frame: Admission to Discharge
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| HFCWO Arm | Hospital Length of Stay | 2.95 days | Standard Deviation 1.01 |
| CPT Arm | Hospital Length of Stay | 5.45 days | Standard Deviation 1.84 |