Studying Umbilical Cord Blood From African-American Donors

Investigation of the Total Nucleated Cell Yield of Cord Blood Units Collected From African-American Donors in Correlation With Gestational and Other Health Variables

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00717535

Enrollment

Registered

2008-07-17

Start date

2005-08-31

Completion date

2009-11-30

Last updated

2013-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Status Unknown

Keywords

health status unknown

Brief summary

RATIONALE: Studying umbilical cord blood in the laboratory and gathering information about current and previous pregnancies from African-American umbilical cord blood donors may help doctors learn more about the umbilical cord blood of these donors. PURPOSE: This clinical trial is looking at umbilical cord blood from African-American donors.

Detailed description

OBJECTIVES: * To correlate the total nucleated cell yield of cord blood units from African-American cord blood donors with gestational history, maternal history, and delivery information. OUTLINE: This is a multicenter study. Donors complete questionnaires about their demographics, maternal history, gestational history, and delivery. Cord blood units (CBU) are collected in utero and transported to the Stem Cell Processing Laboratory where they are evaluated for CBU volume and cell count (i.e., total nucleated cell yield) and cryopreserved. The study results will then be used to devise future interventional strategies to improve the yield of nucleated cells of CBU.

Interventions

OTHERcryopreservation

OTHERquestionnaire administration

OTHERstudy of socioeconomic and demographic variables

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Yes

Inclusion criteria

DISEASE CHARACTERISTICS: * African-American participant in the National Marrow Donor Program cord blood collection protocol C-2844 * Recruited from the Labor and Delivery Suites of the Detroit Medical Center or its affiliated sites PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

Design outcomes

Primary

Measure	Time frame
Correlation between total nucleated cell yield of cord blood units and gestational history, maternal history, and delivery information	Within a year
Improvement in total nucleated cell yield of cord blood units from African-American donors	Within a year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026