Acute Coronary Syndrome
Conditions
Keywords
acute coronary syndromes, quality improvement
Brief summary
The main hypothesis to be tested is that the use of a quality improvement programme will lead to measurable improvements in the management of care and use of evidence based treatments for patients presenting to hospital with non-ST elevation acute coronary syndromes.
Interventions
BEHAVIORALQuality Improvement Programme
Quality Improvement training programme
Sponsors
Uppsala University
GlaxoSmithKline
Royal Brompton & Harefield NHS Foundation Trust
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 80 Years
Healthy volunteers
No
Inclusion criteria
Patients with a good clinical history of ACS and at least one of the following: * New or transient ST or T wave changes on the ECG consistent with acute myocardial ischaemia * Elevation of troponin or other cardiac markers to levels indicative of myocardial necrosis according to local laboratory values
Exclusion criteria
* Evidence of persistent ST elevation on the ECG * Use of early reperfusion therapy * Patients \>80 years * Patients transferred from another hospital
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite of 7 outcome measures to assess aggregate potential for improvement in care using the QI programme:1:risk stratification within 24 hrs, 2:early coronary angiography, 3:anticoagulation, 4:beta-blockers, 5:statins, 6:ACE-inhibitors, 7:Clopidogrel | 10 months |
Secondary
| Measure | Time frame |
|---|---|
| Estimated costs of care for patients | 10 months |
| Estimated costs and economic evaluation of potential cost-effectiveness of QI programme | 10 months |
| Clinical outcomes at discharge including death and myocardial infarction | 10 months |
Countries
France, Italy, Poland, Spain, United Kingdom
Contacts
Primary ContactMarcus D Flather
Backup ContactDaphne Babalis
Outcome results
None listed