Syncope
Conditions
Brief summary
Heat stress reduces the central blood volume and causes orthostatic intolerance. The hypothesis is that infusion of volume may reduce effects of orthostatic stress during heat stress.
Interventions
PROCEDUREIntravascular volume administration
Infusion of colloid to reestablish CVP under heat stress
Sponsors
Rigshospitalet, Denmark
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Age \> 18 \< 40
Exclusion criteria
* Abnormal medical history
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac filling pressure in relation to cardiac SV | with varying degress of lower body negative pressures |
Countries
Denmark
Outcome results
None listed