The Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Excision of Ovarian Cyst

The Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Exc

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00713778

Enrollment

192

Registered

2008-07-11

Start date

2003-11-30

Completion date

2008-05-31

Last updated

2008-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Cysts

Keywords

Ovarian Cysts, Electrocoagulation, Ovarian Function Tests, Laparoscopy

Brief summary

The purpose of this study is to investigate the impact of electrocoagulation on ovarian reserve after laparoscopic excision of ovarian cyst and the possible mechanisms.

Detailed description

Laparoscopic cystectomy is currently considered the treatment of choice in women with benign ovarian cysts and has gained increasing acceptance among gynecological surgeons(1). However, the safety of this technique in terms of ovarian damage to the operated gonad has recently been questioned. In the present study, with the combined use of serum hormonal evaluation and ultrasound examination, we planned to prospectively investigate the ovarian reserve after the excision of benign ovarian cysts. The damage to ovarian reserve will be evaluated through a 12-months follow-up after the application of bipolar, ultrasonic scalpel electrocoagulation or suture during ovarian cystectomy

Interventions

PROCEDUREOvarian cystectomy

Laparoscopic ovarian cystectomy using bipolar

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* Age 18-40 years * Uni/bilateral ovarian cyst(s) without clinical and sonographic suspicion of ovarian cancer * Regular menstrual cycles defined as cycle length between 25 and 35 days in the 6 months before surgery * Agreement to be enrolled in the study

Exclusion criteria

* Prior ovarian surgery * Surgical necessity to perform adnexectomy * Known endocrine disease * Post operative pathologic diagnosis was not benign ovarian cyst * Oral contraceptive use before surgery

Design outcomes

Primary

Measure	Time frame
Serum FSH and E2 assays	12 months

Secondary

Measure	Time frame
Transvaginal ultrasound examinations for basal antral follicle number, mean ovarian diameter and peak systolic velocity	12 months

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026