Methicillin-Resistant Staphylococcus Aureus
Conditions
Keywords
Methicillin resistance
Brief summary
The purpose of this study is to examine treatment method of Methicillin-resistant Staphylococcus aureus (MRSA) decolonization in patients.
Detailed description
Decolonization therapy is indicated for management of patients with MRSA. Theraworx is reported to be an effective antimicrobial against multiple organisms. In this study, patients with positive MRSA colonization culture will be treated with Theraworx to evaluate decolonization duration capability.
Interventions
OTHERTheraworx
Theraworx swab intranasal BID for 5 days
DRUGmupirocin antibiotic ointment
mupirocin antibiotic ointment swab intranasal BID for 5 days
Sponsors
Mercy Research
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Positive MRSA culture
Exclusion criteria
* Patients currently on or start antibiotic therapy directed for MRSA.(Prophylaxis antibiotic for surgical procedure not considered therapy.) * Patients with MRSA infected wounds * Patients under the age of 18 years * A woman currently pregnant or nursing a child * Patients participating in another study within 30 days of randomization
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evidence of decolonization confirmed by intranasal culture | Up to 14 days post treatment (+/- 1-2 days) |
Secondary
| Measure | Time frame |
|---|---|
| Economic-Cost comparison of treatment Evidence of decolonization | 5 days of treatment |
Outcome results
None listed