Speech and Language Therapy After Stroke

Neurophysiological Measurement in Aphasia Treatment

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00713050

Enrollment

Registered

2008-07-11

Start date

2007-08-31

Completion date

2012-01-31

Last updated

2013-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke

Keywords

stroke, aphasia, imitation, mirror neuron

Brief summary

Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.

Detailed description

Detailed information will follow in the next progress report.

Interventions

BEHAVIORALImitate Therapy

Imitation-based computer therapy

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. Single ischemic infarction in the MCA territory involving the cerebral cortex (confirmed by CT or MRI) 2. Aphasia 3. Visual attention and language comprehension sufficient to perform imitation fMRI tasks 4. Right handed (prior to stroke)

Exclusion criteria

Exclusions to the study are people with cardiac pacemakers, claustrophobia, neurosurgical clips, or cognitive impairments too severe to permit cooperation with cognitive tasks in an MRI scanner.

Design outcomes

Primary

Measure	Time frame
Changes in scores on Western Aphasia Battery	Four months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026