Effect of Montelukast on Basophils, In-vitro

The Effect of Montelukast In-vitro on Basophil Histamine and Leukotriene, IL-4 Adn IL-13 Release in Subjects With Allergic Rhinitis or Allergic Asthma

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00710450

Enrollment

Registered

2008-07-04

Start date

2008-05-31

Completion date

2011-09-30

Last updated

2011-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Asthma, Allergic Rhinitis

Keywords

IL13, leukotriene, histamine, IL4, Must be allergic asthma or allergic rhinitis

Brief summary

Subjects with either allergic asthma or allergic rhinitis will be recruited to obtain blood. This blood will be used to be stimulated with to whatever the patient allergic. In the laboratory, this stimulated blood will be measured for histamine, leukotrienes, IL-13 and IL-3. These are chemicals responsible for allergy symptoms.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

12 Years to No maximum

Healthy volunteers

Inclusion criteria

* Allergic asthma or allergic rhinitis * age 12+

Exclusion criteria

* smokers

Design outcomes

Primary

Measure	Time frame
Histamine Release	during the assay portion.

Secondary

Measure	Time frame
Cytokine release. IL-13, IL-4 and leukotriene	assay portion

Countries

United States

Outcome results