Coronary Syndrome
Conditions
Keywords
stenosis, coronaropathy, stent, bypass surgery, suspect, known
Brief summary
Many recent publications have reported encouraging results on diagnostic cardiac multislice CT performance in 1) coronary artery disease, 2) coronary arterial bypass graft potency and 3) intrastent restenosis. These single center studies were made on a limited number of patients (range, 50-130) and focused mainly on one of the indications mentioned above. Moreover, results were often given after exclusion of low quality examinations. At last, no study has compared the diagnostic performance of the different CT systems '16, 40 and 64) in these populations.
Detailed description
These single center studies were made on a limited number of patients (range, 50-130) and focused mainly on one of the indications mentioned above. Moreover, results were often given after exclusion of low quality examinations. At last, no study has compared the diagnostic performance of the different CT systems '16, 40 and 64) in these populations.
Interventions
PROCEDUREmultislice coronary scan
multislice coronary scan
Sponsors
Assistance Publique - Hôpitaux de Paris
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients' ≥18 years, of both sexes * Coronary angiography in patients with suspected of known CAD, instable clinical conditions. * Clinical status allowing performance of coronary angiography 48 à 72h after CT examination * Informed consent signed by patient
Exclusion criteria
* Patients in whom clinical status does not allow delayed coronary angiography * Irregular heart rate, in particular atrial fibrillation * Renal insufficiency (serum creatinine \>150 µmol/l * Radiology examination with use of iodin agent with 48h before) CT coronary * K now intolerance to iodin agents * Patients unable to hold breathing \< 20 seconds * Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specificity and sensibility of scanner | visit 1 |
Secondary
| Measure | Time frame |
|---|---|
| Quality of coronary scanner imaging | visit 1 |
Countries
France
Outcome results
None listed