Levels of Circulating T Cells Expressing VLA-1 Collagen Receptors

VLA-1 Receptors on Peripheral T Cells in Ischemic Heart Disease Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00708838

Enrollment

151

Registered

2008-07-02

Start date

2002-01-31

Completion date

2007-02-28

Last updated

2008-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Heart Disease

Brief summary

The examination of the percentage of peripheral T cells carrying VLA-1 in ischemic heart disease patients. The hypothesis is that the percentage levels of cells carrying this integrin rise according to the severity of the ischemic heart disease.

Detailed description

Atherosclerosis is considered an inflammatory disease in which lymphocytes have an important role. The study was disigned to find out the changes in T cell levels carrying VLA-1 involvement in this process.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* clinical diagnosis of acute MI for group 1 * clinical diagnosis of ACSl for group 2 * clinical diagnosis of Chronic Heart Disease for groups 3 and 4 * Chest pain but normal heart scan for group 5

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame
The differance in percentage of T cells in the 5 different groups involved.	2002-2006

Outcome results