A Multi-Dose Study With a Treatment for Open-Angle Glaucoma

Status

Withdrawn

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00705770

Enrollment

Registered

2008-06-26

Start date

2008-05-31

Completion date

2008-07-31

Last updated

2012-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open-Angle Glaucoma

Keywords

Open-Angle Glaucoma, Intraocular Pressure, Anecortave Acetate

Brief summary

The purpose of this study is to determine whether Anecortave Acetate is effective for lowering intraocular pressure caused by open-angle glaucoma.

Interventions

DRUGAnecortave Acetate

Low dose Sustained release depot suspension

DRUGPlacebo

Placebo treatment with vehicle

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients at least 18 years old with a clinical diagnosis of Open-Angle Glaucoma for at least 6 months and currently treated with a monotherapy hypotensive medication

Exclusion criteria

* Prior angle surgery in the study eye, severe visual field loss in either eye, and any other form of glaucoma besides open-angle glaucoma

Design outcomes

Primary

Measure	Time frame
Mean Intraocular Pressure	6 months

Secondary

Measure	Time frame
Percent of patients with therapeutic benefit, number and percent of treatment failure and time to treatment failure	6 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026