Planning Margin Requirements for Pediatric Radiation Oncology

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00704613

Enrollment

375

Registered

2008-06-25

Start date

2008-03-31

Completion date

2011-07-31

Last updated

2011-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Radiation

Brief summary

The planning target volume (PTV) and planning organ at risk volume (PRV) margins used for pediatric radiation therapy are empiric, and quantitative assessment of these margins is needed to improve therapy planning and delivery.

Detailed description

Data will be gathered to develop a model to quantify the setup margin (SM) portion of the planning target volume (PTV) margin for pediatric tumor sites according to age, localization technique, treatment position, and the use of general anesthesia. Patient specific PTV and PRV margin recommendations will be developed based on the number of participants.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients will receive conformal or intensity-modulated radiation therapy (3D or IMRT). * Research participant or legal guardian/representative gives written informed consent.

Exclusion criteria

* Unwillingness of research participant or legal guardian/representative to give written informed consent

Design outcomes

Primary

Measure	Time frame
Acquire data to develop setup margin (SM) portion of the planning target volume (PTV) margin for pediatric tumor sites according to age, localization technique, treatment position, and the use of general anesthesia.	4 year

Secondary

Measure	Time frame
Estimate the number of patients required to develop a patient specific PTV and RTV margin recommendations.	4 year

Countries

United States

Outcome results