Immunoregulation of Periodontal Disease

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00702429

Enrollment

Registered

2008-06-20

Start date

2008-08-31

Completion date

2010-07-31

Last updated

2014-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Disease

Brief summary

Our design is to test in hospital practice a selection of immune parameters that could assess the pathophysiology and progression of periodontal lesions.

Detailed description

These parameters will be measured in 25 healthy volunteers and 25 moderate-to severe periodontal disese patients. Phagocytes will be tested phenotypically and functionally, both ex vivo and in vitro.

Interventions

OTHERBlood sampling

Analysis of the PNN, analysis of the monocytes

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Persons appearing spontaneously at the consultation of parodontologie for parodontale disease, * persons agreeing to undergo a sampling of blood intended for the search

Exclusion criteria

* Presence of a chronic or pointed pathology, * an age 18-year-old subordinate or 65-year-old superior, * pregnant women,

Design outcomes

Primary

Measure	Time frame
Percentage of positive cells and intensity of expression for the molecules of surface studied there cytometric in stream	24 months

Secondary

Measure	Time frame
Rate of secretion of cytokines and the other substances	24 months
Detection and quantification of ARN messengers	24 months

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026