Burns
Conditions
Keywords
sodium heparin, burns of the skin
Brief summary
Burns are injuries caused by agents thermal, chemical, electrical or radioactive who act in the tissue lining of the human body and may partially or totally destroy the skin and its annexes, to the deeper layers, as subcutaneous tissue, muscles, tendons and bones . Studies show that topical heparin has, in addition to the already known anticoagulant activity, anti-inflammatory properties, analgesic, and neoangiogenic, stimulating blood flow and increasing the repair of the fabric as well as the restoration of collagen and reepiteliztion. Moreover, the use of heparin reduces the need for painful medical procedures, as debridations, surgeries and transplants The intention of this work is to verify the effectiveness and safety of sodium heparin in the treatment of burns of the skin.
Detailed description
Patients with burns that come to the emergency room will be informed about the Inclusion Criteria * Patients aged above 12 years who have suffered thermal burns of 2nd degree burns or mixed 2 and 3 degrees in up to 10% of body surface and indication of outpatient treatment. Exclusion Criteria * Area burned more than 10% of body surface * the presence of the 3 rd degree burns * burns in the face or genitals * burns in poly-traumatized * respiratory injury * disorders of coagulation * thrombocytopenia * erosive gastro cases * clinically relevant bleeding * hypersensitivity to anticoagulants * liver disease * nephropathy * diabetes * 35 * serious allergy * descontrole emotional * pregnancy * anemia
Interventions
patients will receive the application of one of two types of heparin directly on the injured area
patients will receive the application of folder water directly on the injured area
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients aged above 12 years who have suffered thermal burns of 2nd degree burns or mixed 2 and 3 degrees in up to 10% of body surface and indication of outpatient treatment.
Exclusion criteria
* Area burned more than 10% of body surface * the presence of the 3 rd degree burns * burns in the face or genitals * burns in poly-traumatized * respiratory injury * disorders of coagulation * thrombocytopenia * erosive gastro cases * clinically relevant bleeding * hypersensitivity to anticoagulants * liver disease * nephropathy * diabetes * 35 * serious allergy * descontrole emotional * pregnancy * anemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary: immediate decrease in pain. Secondary: analgesic request for 10 minutes after application of heparin, signs of intolerance and adverse events. | healing |
Countries
Brazil