Rectal Cancer
Conditions
Keywords
low or high ligation
Brief summary
The purpose of this study is to evaluate the defecatory function when nerve fibers around the inferior mesenteric artery(IMA) and left colic artery(LCA) are preserved(so called low ligation ) or not(high ligation) in the rectosigmoid and rectal cancer surgery.
Detailed description
Fecal incontinence after anterior resection are often observed. Whether or not postoperative bowel function is influenced by the preservation of nerve fibers around the root of IMA and LCA (low ligation) is still unknown. So in this randomized controlled trial, we evaluate the efficacy of low ligation in terms of the bowel function.
Interventions
PROCEDUREpreservation of nerve fibers around IMA
low ligation
PROCEDUREresection of nerve fibers around IMA
high ligation
Sponsors
Wakayama Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* On the basis of whether anterior resection was anticipated at WMUH for rectosigmoid and rectal cancer, and appropriate informed consent was obtained.
Exclusion criteria
* Patients who could not respond to medical interview for own bowel function * Patients without an informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of bowel function | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| comparison of leakage rate | 2 weeks |
Countries
Japan
Outcome results
None listed