Immune Response and Cytomegalovirus in Intensive Care Unit (ICU) Patients

Cellular Immunity, Cytomegalovirus Infection and Septic Shock in ICU Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00699868

Acronym

2006/25

Enrollment

Registered

2008-06-18

Start date

2008-03-31

Completion date

2011-08-31

Last updated

2012-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cytomegalovirus Infection

Brief summary

This prospective study evaluate the immune status of patients admitted in ICU.CMV remains dormant in the body, but in people with immune deficiency, CMV could reactivate and cause life-threatening pneumonia.

Detailed description

Candidates will be screened with medical history and blood tests.Then, 2 groups of 20 patients (with or without CMV reactivation) matched for CMV status will be compared for their immune system against CMV.

Interventions

OTHERSampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings

Sampling of blood

Study design

Intervention model

PARALLEL

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age more than 18-year-old * Informed consent

Exclusion criteria

* minors, * pregnant or lactating women, * adults under guardianship, * immunosuppression at the entrance to resuscitation, * AIDS

Design outcomes

Primary

Measure	Time frame
Bring to light the quantitative and qualitative immunological modifications of the present cells NK before the arisen of an infection to CMV	24 months

Secondary

Measure	Time frame
Bring to light the quantitative and qualitative immunological modifications of cells NK in the consequences of an infectious shock	24 months

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026