Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00699530

Enrollment

Registered

2008-06-18

Start date

2008-05-31

Completion date

2016-11-30

Last updated

2017-12-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperprolactinemia, Insulin Resistance

Keywords

Prolactin, Insulin resistance, Glucose tolerance, Body Composition, Substrate metabolism

Brief summary

The purpose of this study is to investigate the effects of chronic elevated levels of Prolactin on metabolism and insulin sensitivity by studying patients with hyperprolactinemia before and after treatment.

Interventions

OTHERCabergoline

Cabergoline 0,25 - 1,0 mg once a week, controlled by our outpatient clinic. The drug regimen is not influenced by participating in this study.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Written consent * Age between 18 and 70 * At diagnose a serum prolactin \> 200 microgram/l (10 U/l)

Exclusion criteria

* Hypothyroidism * Use of any medication * Pregnancy

Design outcomes

Primary

Measure	Time frame
Insulin sensitivity	Before and after treatment

Secondary

Measure	Time frame
QoL, body composition, intrahepatic and intramyocellular fat, substrate metabolism, glucose tolerance	Before and after treatment

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026