Fibromyalgia
Conditions
Brief summary
Fibromyalgia (FM) syndrome is a chronic pain condition.Repetitive trans-cranial magnetic stimulation (rTMS) was thus suggested in this indication.
Detailed description
We recently demonstrated that these patients exhibit significant perfusion abnormalities in regions of the brain known to be involved in sensory and affective-attentional dimensions of pain processing. These results, in agreement with previous functional magnetic resonance imaging reports, confirm the hypothesis of central sensitization, which provides the rationale for prescription of centrally acting analgesic agents in patients with severe FM.
Interventions
Stimulation to white
Sponsors
Assistance Publique Hopitaux De Marseille
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Female or male patient, aged from 18 to 65 years * Patient presenting a primary fibromyalgia answering the criteria of the ACR * At present painful patient with a digital echelle of the briefing inventory bread superior or equal to 4/10 * Patient presenting a stable treatment since at least 1 less
Exclusion criteria
* Patient minor * pregnant woman * women in age to procreate without contraception * patient deprived of freedom further to a court or administrative order * patient presenting a secondary fibromyalgia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analgesic efficiency | 36 months |
Secondary
| Measure | Time frame |
|---|---|
| Additional evaluation of the pain | 36 months |
| Evaluation of the quality of life | 36 months |
| Evaluation of the tolerance of the treatment | 36 months |
Countries
France
Outcome results
None listed