Vitiligo
Conditions
Keywords
Vitiligo
Brief summary
308 nm excimer lamp and 308 nm excimer laser have both provide interesting results in treating vitiligo. They have the same wavelength but the type of emission of the photons is different. To date there is no direct comparative data concerning these two devices in this indication. The aim of the study is to make an intra-individual prospective comparison between these two phototherapies.
Interventions
RADIATION308nm excimer lamp
50 mJ/cm² below the MED (minimal erythemal dose) and progressive increase Twice a week for 12 weeks
RADIATION308nm excimer laser
50 mJ/cm² below the MED (minimal erythemal dose) and progressive increase Twice a week for 12 weeks (same doses will be used between the 2 arms)
Sponsors
Centre Hospitalier Universitaire de Nice
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient above 18 * vitiligo for more than 3 months * at least 2 vitiligo symmetric patches more than 10cm² * to read and understand the inform consent * to have a social security number * non pregnant for women
Exclusion criteria
* pregnant women * keloids * history of radiotherapy or skin cancer in the treated areas * treatment for vitiligo in the past 4 weeks * phototherapy in the past 12 weeks; history of photodermatosis * treatment inducing photosensibilization * immunosuppression * patient who participated in a study in the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Repigmentation rate in the treated areas | 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Tolerance and safety of the treatments | 12 weeks |
Countries
France
Outcome results
None listed