High Fat Diet: Oxidative and Cardiovascular Effects

High Fat Diet: Oxidative Effects and Cardiovascular Risk

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00696228

Acronym

AFN

Enrollment

144

Registered

2008-06-12

Start date

2008-08-31

Completion date

2013-12-31

Last updated

2020-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Brief summary

To test the effects of a modified Atkins high fat diet on endothelial function, insulin resistance and energy balance.

Detailed description

To test the effects of a modified Atkins high fat diet on endothelial function, insulin resistance and energy balance.

Interventions

DIETARY_SUPPLEMENTPlacebo

Placebo

DIETARY_SUPPLEMENTMUFA

MUFA

DIETARY_SUPPLEMENTPUFA

PUFA

DIETARY_SUPPLEMENTSFA

SFA

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

FEMALE

Age

21 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI 30-39.9 * Female * Age 21-40

Exclusion criteria

* Smoker * Comorbid Disease

Design outcomes

Primary

Measure	Time frame
endothelial function	4 months

Secondary

Measure	Time frame
energy balance and body composition	4 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026