Schizophrenia
Conditions
Keywords
schizophrenia, neuroplasticity, sensory gating, cognitive impairment, MEG, Disorders with Psychotic Features
Brief summary
The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.
Detailed description
Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. In this study we compare effects of two computer-aided training programs. One focused on auditory perception and processing as a basic ability underlying higher order information processing. The other training involves a variability of cognitive abilities. Both trainings are computer-aided and time-intensive, including up to twenty sessions within four weeks.
Interventions
BEHAVIORALBrain Fitness Program
Computer-aided cognitive program designed for intensive training of auditory perception, memory and attention
BEHAVIORALCogpack
Computer-aided cognitive program for cognitive abilities
Sponsors
German Research Foundation
University of Konstanz
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
No minimum to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Clinical diagnosis of schizophrenia and disorders with psychotic features * Intact hearing abilities
Exclusion criteria
* Mental retardation * Age over 60 * Insufficient German language knowledge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Event related potential MEG, test scores in word fluency and verbal learning tasks | pre and post intervention |
Secondary
| Measure | Time frame |
|---|---|
| Symptom severity, GAF score | pre and post intervention |
Countries
Germany
Outcome results
None listed