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Vitamin D and Type 2 Diabetes - a Cross Sectional Study

Vitamin D and Type 2 Diabetes - a Cross Sectional Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00695474
Enrollment
150
Registered
2008-06-11
Start date
2008-06-30
Completion date
2009-04-30
Last updated
2009-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypovitaminosis D, Type 2 Diabetes Mellitus

Keywords

Hypovitaminosis D, Type 2 diabetes, Glycemic control, Inflammation, Blood pressure

Brief summary

The purpose of the study is to describe vitamin D status among patients with type 2 diabetes and to determine the association between serum 25-hydroxyvitamin D and glycemic control, markers of inflammation and blood pressure

Detailed description

It has been estimated that 1 billion people worldwide have vitamin D deficiency or insufficiency. It is well known that vitamin D deficiency causes osteoporosis, increases the risk of fracture and causes muscle weakness. But there is now evidence that calcium malnutrition and hypovitaminosis D are predisposing conditions for various common chronic diseases such as malignancies (particularly colon, breast and prostate) chronic inflammatory and autoimmune disease (inflammatory bowel disease, multiple sclerosis) as well as metabolic disorders (metabolic syndrome, hypertension). It has also been reported that vitamin D deficiency may predispose to glucose intolerance, altered insulin secretion and type 2 diabetes mellitus. The purpose of this study is to determine vitamin D status among type 2 diabetics in our outpatient clinic and examine the relationship between vitamin D status , calcium and phosphorous metabolism, inflammatory markers, glycemic control, blood pressure and lipid profile. Moreover the patients are asked to answer a questionnaire regarding lifestyle, exercise, sun exposure and food intake.

Interventions

None listed

Sponsors

Aarhus University Hospital
CollaboratorOTHER
Regionshospitalet Silkeborg
CollaboratorOTHER
University of Aarhus
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* Type 2 diabetes mellitus * Patients of Danish extraction * Written consent

Exclusion criteria

* Renal failure (Urea \> 12 mmol/l) * Age \< 18 years * malabsorption

Design outcomes

Primary

MeasureTime frame
Vitamin D status and its association with inflammation, glycemic control, lipids and blood pressure.December 08

Secondary

MeasureTime frame
Lifestyle (exercise, sun exposure, food intake)December 08

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026