Constraint-Induced (CI) Movement Therapy for Progressive Multiple Sclerosis (MS)

Constraint-Induced Movement Therapy Trial for Progressive Multiple Sclerosis

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00695084

Enrollment

Registered

2008-06-11

Start date

2007-03-31

Completion date

2008-04-30

Last updated

2008-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis

Keywords

multiple sclerosis

Brief summary

This trial will evaluate whether progressive multiple sclerosis associated with hemiparesis may benefit from Constraint-Induced Movement Therapy.

Detailed description

Constraint-Induced Movement Therapy was developed to treat stroke hemiparesis. Due to the similarity between multiple sclerosis and stroke in terms of chronic motor deficit, this trial will attempt to determine whether multiple sclerosis may benefit similarly from Constraint-Induced Movement Therapy.

Interventions

BEHAVIORALConstraint-Induced Movement Therapy

Intensive practice with the hemiparetic arm for 30 contact hours

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Chronic upper extremity motor deficit due to multiple sclerosis

Exclusion criteria

* Relapse within 3 months of planned enrollment.

Design outcomes

Primary

Measure	Time frame
Improvement on the Motor Activity Log	One year

Secondary

Measure	Time frame
Improvement on the Wolf Motor Function Test	Pre to post-treatment

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026