Orthostatic Intolerance, Postural Tachycardia Syndrome, Sleep Disorders
Conditions
Keywords
Sleep, Orthostatic tachycardia, POTS
Brief summary
We propose to use actigraphy (measured by activity watches) as a tool to quantify sleep disturbances in patients with orthostatic intolerance compared with healthy control subjects. In this pilot study, we will test the null hypothesis (Ho) that there are no differences in the sleep quality between patients with orthostatic intolerance and healthy control subjects.
Detailed description
We propose to use actigraphy (measured by activity watches) as a tool to quantify sleep disturbances in patients with orthostatic intolerance compared with healthy control subjects. In this pilot study, we will test the null hypothesis (Ho) that there are no differences in the sleep quality between patients with orthostatic intolerance and healthy control subjects.
Interventions
DEVICEActigraphy Watch (motion sensors) with light sensors - ActiWatch from Minimitter
Watch to be worn on wrist for 7 days (except in water) that will measure activity/movement.
Sponsors
National Center for Research Resources (NCRR)
Satish R. Raj
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Diagnosed with orthostatic intolerance by the Vanderbilt Autonomic Dysfunction Center * Control subjects will be free of orthostatic intolerance and other major medical problems, free of medications during the study * Age between 18-65 years * Male and female subjects are eligible. * Able and willing to provide informed consent
Exclusion criteria
* Overt cause for postural tachycardia (such as acute dehydration) * Self-report of pregnancy * Inability to give, or withdrawal of, informed consent * Other factors which in the investigator's opinion would prevent the subject from completing the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep Latency | 1 week |
Secondary
| Measure | Time frame |
|---|---|
| Sleep Efficiency | 1 week |
| Wake After Sleep Onset | 1 week |
Countries
United States
Outcome results
None listed