Open-angle Glaucoma, Oular Hypertension
Conditions
Keywords
Anecortave acetate, Open-angle glaucoma, IOP, OHT
Brief summary
The purpose of this study was to evaluate the safety and intraocular-lowering efficacy of anecortave acetate depot when administered by anterior juxtascleral depot (AJD) for the treatment of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Interventions
Single administration by anterior juxtascleral depot
Single administration by anterior juxtascleral depot
DRUGAnecortave Acetate Sterile Suspension, 75 mg/mL
Single administration by anterior juxtascleral depot
Single administration by anterior juxtascleral depot
Sponsors
Alcon Research
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients 18 years of age or older with open-angle glaucoma (with or without pigment dispersion or pseudoexfoliation) or ocular hypertension. * Other protocol-defined inclusion criteria may apply.
Exclusion criteria
* Patients with any form of glaucoma other than open-angle. * Other protocol-defined
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Intraocular Pressure at 8 am | Up to 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Percent of Patients Who Remained Rescue Medication-Free at Month 3 (8 am) | Month 3, 8 am |
Countries
United States
Outcome results
None listed