Resistant Starch on Glucose and Insulin Sensitivity in Individuals With Type 2 Diabetes

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00691249

Enrollment

Registered

2008-06-05

Start date

2008-05-31

Completion date

2009-06-30

Last updated

2009-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperglycemia

Keywords

Diabetes, Diet, Fiber

Brief summary

This study will test the effects of resistant starch type 4 on blood sugar and hunger in adults with Type 2 diabetes.

Detailed description

To measure the blood glucose response, after an overnight fast, blood samples will be collected before eating and 15, 30, 45, 60, 90, and 120 minutes after eating each bar. The incremental area under the curve was used to calculate glycemic index. The investigators will also measure the second meal effect by measuring the metabolic response (glucose, insulin, and gut hormones) after a standardized lunch two hours following the first assessment.

Interventions

DIETARY_SUPPLEMENTResistant Starch Type 4-Raw

Low Dose- 70g bar

DIETARY_SUPPLEMENTResistant Starch Type 4-Cooked

Low Dose- 70g bar

DIETARY_SUPPLEMENTShredded Wheat

70g bar

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Type 2 Diabetics

Exclusion criteria

* Diagnosed with other metabolic disorders * Allergies to wheat * Non-smokers

Design outcomes

Primary

Measure	Time frame
Post-Prandial metabolism	Acute -- fasting, 15, 30, 45, 60, 90 and 120 minutes post-ingestion

Secondary

Measure	Time frame
Satiety	Early morning - Midafternoon

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026