Expressive Language and Cognitive Early Development in Very Low Birth-Weight Preterm Toddlers

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00689676

Enrollment

Registered

2008-06-03

Start date

2006-01-31

Completion date

2007-10-31

Last updated

2009-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prematurity

Keywords

expressive language, cognition, early development, very low birt weight, prematurity

Brief summary

The aim of the present study is to describe the performance of very low birth-weight preterm toddlers regarding expressive language and cognitive development during sensorimotor and beginning of pre-operational periods, as well as to compare the performance presented by these children to that presented by their full-term peers, according to Genetic Epistemology theoretical principles. The hypothesis of this study is that very-low birth weight preterms would present a poorer performance, concerning expressive language and cognition development,than their full-term peers.

Detailed description

Very low birth weight preterm infants are known to have risks of cognitive and behavioral problems, including learning difficulties, attention deficits and hyperactivity, as well as neuromotor deficits. Moreover, they are reported to have a high risk of speech and language impairments up to school age, even in cases where major neurological abnormalities are excluded. Impairments have been reported both in receptive and expressive language and, more specifically, in morphosyntax and naming.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Months to 18 Months

Healthy volunteers

Yes

Inclusion criteria

Study Group: Inclusion Criteria: * gestational age lower than 34 weeks (according to the date of last menstrual period - DLMP); * birth weight equal or lower than 1500g; * exposed only to Brazilian Portuguese

Exclusion criteria

* presence of major malformations, genetic syndromes, severe neonatal asphyxia, hearing impairment or visual impairment. Control Group: Inclusion Criteria: * gestational age higher than 38 weeks; * adequate for gestational age; * birth weight higher than 2500g up to 3999g * exposed only to Brazilian Portuguese

Design outcomes

Primary

Measure	Time frame
Performance on monthly observations carried out after the initial evaluation	18 months

Countries

Brazil

Outcome results