Comparison of On-line and Off-line Measurements of Exhaled Nitric Oxide (NO)

Comparison of On-line and Off-line Measurements of Exhaled NO

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00686309

Enrollment

200

Registered

2008-05-29

Start date

2010-07-31

Completion date

2011-07-31

Last updated

2009-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma, Primary Ciliary Dyskinesia

Keywords

exhaled NO, off line, on line, comparison, Bland altman method

Brief summary

Asthma is a major health problem worldwide. The measurement of fractional exhaled nitric oxide (FENO) has been established as a valuable non invasive and simple tool in the diagnosis of asthma and may also act as a useful surrogate inflammatory marker on which to base treatment decisions in asthma management algorithms. The measurement is useful also in other respiratory diseases. Current methods of measuring FENO include on line measurements by heavy duty expensive analyzers which are not widely and easily available. Off line measurements of breath samples which can be analysed later may be a simple solution. We hypothesize tha toff line measurements of NO will be as reliable and valid as those measured on-line

Interventions

None listed

Study design

Observational model

CASE_CROSSOVER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Volunteer to participate * Filed a short health questionnaire

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame
Off line measurement of exhaled NO	Two types of breathing in the same day

Countries

Israel

Contacts

Primary ContactIsrael Amirav, MD

amirav@012.net.il972-4-682-8712

Outcome results