Attention Deficit Disorder With Hyperactivity
Conditions
Keywords
Attention, Deficit, Disorder, Hyperactivity, cerebellum, alteration, fronto-cerebello-frontal loops
Brief summary
The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.
Detailed description
ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.
Interventions
OTHERImaging
neuropsychological evaluation and Imaging with magnetic resonance (MRI)
Sponsors
University Hospital, Bordeaux
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
Patient with ADHD : * Diagnosis of ADHD * 18 - 35 years old Healthy volunteer : * 18 - 35 years old * no ADHD diagnosed
Exclusion criteria
* Associated neurological or psychiatric pathologies * Pregnant woman * MRI counter indication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fractional anisotropy coefficient if fronto-cerebello-frontal loops. | visite 1 |
Countries
France
Outcome results
None listed