HIV Infections
Conditions
Keywords
Substance Abuse, Adolescent community reinforcement approach, Adolescent Risk Behavior Assessment, Child and Adolescent Services Assessment, Cognitive behavioral therapy, Cognitive Therapy Rating Scale, Individual behavior therapy, Individual cognitive problem solving, Motivational enhancement therapy, HIV-Positive Youth With Substance Abuse, Complementary Therapies
Brief summary
This is an exploratory study that will adapt and test a combined cognitive behavioral treatment and contingency management intervention for alcohol and/or marijuana abuse for use in HIV-infected adolescents.
Interventions
BEHAVIORALFocus Group
Focus group using and collecting feedback on the CBT/CM intervention.
BEHAVIORALFirst Intervention Trial
Intervention will comprise of approximately 15 weekly sessions. * Exit interviews at the end of each session will assess acceptability, feasibility, and relevance of the intervention. * Quantitative assessment (ACASI) pre and post intervention will document immediate changes in substance use, sexual risk, and adherence to medical care. * Qualitative feedback from interviews with mental health providers and study coordinators will address acceptability and feasibility.
BEHAVIORALIntervention Trial 2
Evaluations/assessments will be similar to those involved for the first intervention trial. Study participants will return for a follow-up visit 3 months after the last intervention session to complete the ACASI.
Sponsors
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)
University of North Carolina, Chapel Hill
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
16 Years to 24 Years
Healthy volunteers
No
Inclusion criteria
* Adolescents between the ages of 16-24 years (inclusive) at the time of informed consent/assent as determined by medical record review or verbal verification from referring professional * HIV-infected and aware of their status as documented by medical record review or verbal verification from referring professional * Receives services at one of the three participating ATN clinic site or their community partners * A score of 2 or greater on the CRAFFT indicating possible alcohol or marijuana use problem or abuse * Alcohol and/or Marijuana Use or Abuse Disorder as indicated by the SSPQ-X * Appropriate for an outpatient or intensive outpatient level of care in accordance with the American Academy of Child and Adolescent Psychiatry practice parameters as decided by site mental health provider in consultation with Drs. Brown and Esposito-Smythers * English-speaking * Ability and willingness to provide informed consent/assent for study participation * Satisfactorily understands the nature of the study and the informed consent process as documented by the Consent Form Comprehension Assessment Questionnaire
Exclusion criteria
* Presence of serious psychiatric symptoms (e.g., active hallucinations, thought disorder) * Visibly distraught (e.g., suicidal, homicidal, exhibiting violent behavior) * Intoxicated or under the influence of alcohol or other substances at the time of study entry
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To adapt a developmentally appropriate CBT/CM intervention for alcohol and/or marijuana abuse for HIV+ youth, relevant to the context of chronic medical care, emotion dysregulation due to frequent co-morbid psychiatric disorders and sexual risk behavior. | 2 years |
| To evaluate the acceptability, feasibility, and effectiveness of the CBT/CM intervention for alcohol and/or marijuana abuse, adherence to medical care, emotion regulation, and safer sexual behavior. | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| To revise the CBT/CM intervention based on information obtained in Phase 1 (this protocol), prepare for Phase 2 (to be supported by NIH), and disseminate the treatment manual to the ATN sites. | 2 years |
Countries
United States
Outcome results
None listed