Cholesteatoma
Conditions
Brief summary
Classical imaging techniques are inaccurate to detect residual cholesteatoma. The aim of our study is to evaluate the value of diffusion-weighted MR imaging and delayed contrast enhanced T1 weighted spin-echo sequences in the detection of residual cholesteatoma in children, in a large serie of surgically verified cases.
Detailed description
Classical imaging techniques are inaccurate to detect residual cholesteatoma. Thin-section CT detects that the postoperative cavity is filled with a soft tissue mass. Classical MR imaging (T2 and T1 weighted spin-echo sequences) can not provide additionnal information about the nature of this filling : cholesteatoma, granulation or fibrous tissue.
Interventions
OTHERMR Imaging
MR imaging in the post operative follow-up of cholesteatoma in children
Sponsors
Assistance Publique Hopitaux De Marseille
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
5 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* Female or male child enters 5 and 18 years * Child having benefited from a surgical operation for cholesteatoma of the average ear acquired or congenital, one-sided or bilateral * Child for whom an additional operating time is indicated * Child without contraindication in the MRI * Child having signed a enlightened assent * Child among whom the parents or the legal representatives signed a enlightened assent
Exclusion criteria
* Child of less than 5 years old and more than 18 years * Child presenting a chronic renal insufficiency * Child for whom an additional operating time is not indicated * Child having a contraindication in the MRI * Child not having signed the assent or the parents of which did not sign the assent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Technical characteristics of the examination MRIs represented by the sensibility and the specificity of the test, with regard to the results stemming from the surgical operation | 24 months |
Secondary
| Measure | Time frame |
|---|---|
| Only a surgical operation will confirm the diagnosis of cholesteatoma doing it again or residual. | 24 months |
| It is necessary to test the following diagnostic method: the analysis of the morphological sequences in T1 and in T2 will allow to appreciate the existence or not of a filling of the cavity tympanique or the mastoïde and to clarify its localization. | 24 months |
Countries
France
Outcome results
None listed