Use of Bone Scintigraphy, CT and MRI in Breast Cancer

Use og Bone Scintigraphy, CT and MRI for Detection of Metastases in Patients With Breast Cancer

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00682253

Enrollment

180

Registered

2008-05-22

Start date

2008-05-31

Completion date

2011-03-31

Last updated

2009-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Neoplasms

Keywords

SPECT/CT, MRI, Breast neoplasms

Brief summary

A new imaging modality combining CT and tomographic bone scintigraphy (SPECT/CT) has enabled the combination of functional and anatomical imaging. Its use in cancer patients has not yet been evaluated or validated against a relative gold stand or clinical follow up. The purposes of this study are: 1: to validate the use of conventional planar bone scintigraphy and SPECT combined with low-dose or diagnostic CT and compare this to 3 Tesla MRI and clinical follow up. 2: to compare the specificity of low-dose and diagnostic CT, respectively, combined with bone SPECT. 3: to construct an algorithm for optimal evaluation of disease dissemination in breast cancer patients

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Histological verified breast cancer * Age 18-80 years * Investigation for metastases using imaging modality/modalities planned * Written consent to participate in trial

Exclusion criteria

* Overweight limiting the use of MRI * Metal parts in body * Claustrophobia * Allergy to contrast agents used in trial * Pregnancy

Countries

Denmark

Contacts

Primary ContactAnni Eskild-Jensen, MD, PhD, DMSci

aej@ki.au.dk+45 8949 2251

Outcome results