Long-Term Outcomes of Alternative Brachytherapy Techniques for Early Prostate Cancer

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00681694

Enrollment

414

Registered

2008-05-21

Start date

2002-03-31

Completion date

2011-03-31

Last updated

2010-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate Cancer

Keywords

brachytherapy, radioactive seed implants

Brief summary

The purpose of this research study is to assess outcomes of treatment for early prostate cancer. Current treatments for early (non-metastatic) cancer may cause long-term impairments in the patients quality of life. In this study we will compare the outcomes of patients treated with two alternative brachytherapy (seed implants) techniques using a series of questionnaires.

Detailed description

Participants will be asked to complete a questionnaire about their health prior to treatment, at 1, 3 and 12 months after treatment and then once a year 4 more times.

Interventions

RADIATIONbrachytherapy

An experimental arm using MRI imaging and excluding the transition zone from the target volume

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Pathological diagnosis of an adenocarcinoma of the prostate * 18 years of age or older * Prior choice of either standard brachytherapy or MRIGPB as primary treatment

Exclusion criteria

* Prior primary therapy (surgery or external beam radiation) for prostate cancer * Current hormone ablation therapy

Design outcomes

Primary

Measure	Time frame
To assess changes in generic and disease specific quality of life over time after treatment with brachytherapy for early prostate cancer	10 years

Secondary

Measure	Time frame
To compare these outcomes after two alternative brachytherapy techniques, standard ultrasound guided brachytherapy and MRI guided prostate brachytherapy (MRIGPB)	10 years
To identify factors associated with specific adverse outcomes.	10 years

Countries

United States

Contacts

Primary ContactJames Talcott, MD, SM

jtalcott@partners.org617-724-5451

Backup ContactAnita Rodrigues

aerodrigues@partners.org

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 8, 2026