Skip to content

Adolescent Substance Abuse: Progressive Treatment

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00680576
Acronym
ADAPT
Enrollment
140
Registered
2008-05-20
Start date
2008-03-31
Completion date
2013-08-31
Last updated
2014-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Substance Abuse

Keywords

adolescent substance abuse

Brief summary

The purpose of this study is to find out more about how to provide effective further treatment for adolescents who have received six weeks of group therapy for substance-use problems and continue to use drugs. Treatments used in the study include a group therapy (MET/CBT), an individual therapy (CBT), and a family therapy (FFT). The study will look at whether abstinence or a very low level of use is a better guide for deciding whether further treatment is needed, how well different combinations of treatment work to reduce substance use, and whether it is possible to predict in advance which adolescents will respond best to which types of treatment. Study investigators expect that a treatment strategy using what is learned about these issues in the first half of the project to develop an adaptive treatment model will work better than a fixed treatment to reduce adolescent substance use.

Interventions

BEHAVIORALCBT, Cognitive Behavioral Therapy

Eight weekly sessions of individual Cognitive Behavioral Therapy, to develop skills enabling adolescents stop or reduce their drug use.

BEHAVIORALFFT, Family Functional Therapy

Eight weekly sessions of Functional Family Therapy designed to strengthen family relationships and build skills to help the adolescent stop or reduce his/her drug use.

Sponsors

Oregon Research Institute
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
13 Years to 18 Years
Healthy volunteers
Yes

Inclusion criteria

1. 13 to 18 years if age 2. Meet DSM-IV (APA, 1994) diagnostic criteria for substance abuse or dependence 3. Live in the Albuquerque metropolitan area or surrounding communities 4. Sufficient residential stability to permit probable contact at follow-up (e.g., not homeless at time of intake).

Exclusion criteria

1. There is evidence of psychotic or organic state of sufficient severity to interfere with the understanding of study instruments and procedures 2. The adolescent is deemed dangerous to self or others during evaluation 3. Services other than outpatient treatment are required for the adolescent (e.g., inpatient, detoxification) 4. Marijuana use is reported as being less than 13% of days in the previous 90 days.

Design outcomes

Primary

MeasureTime frame
Urine drug screensPretx, 6, 14 and 22 weeks, 3 and 6 months after initial treatment session

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026