Pregnancy/Implantation Rates Using a Day 3 Score Versus Graduated Embryo Score Plus a Biochemical Marker (sHLA-G)

Pregnancy and Implantation Rates When Embryos Are Selected Based on a Single Day 3 Score (Day 3)vs Graduated Embryo Score(GES) Plus Soluble Human Leukocyte Antigen-G Expression.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00680238

Enrollment

214

Registered

2008-05-20

Start date

2004-06-30

Completion date

2007-06-30

Last updated

2008-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

Pregnancy, implantation, miscarriage, sHLA-G

Brief summary

Objective: To compare pregnancy rates and implantation rates when embryos are selected based on a single Day 3 (D.3) score vs. a GES score plus sHLA-G expression.

Detailed description

Comparing pregnancy rates and implantation rates when embryos are selected using the most common criteria for embryo selection on day 3 - the morphology-(number of blastomere, their shape and size and the percentage of fragmentation)vs a graduated embryo score accumulated over 72 hours and the expression of sHLA-G at 44-46 hours post fertilization.

Interventions

DRUGHuman derived FSH

Customized for each patient

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Self paying ART patients

Exclusion criteria

* Abnormal uterus * Specific Immunologic factors

Design outcomes

Primary

Measure	Time frame
Pregnancy and implantation rates	12 weeks

Secondary

Measure	Time frame
Miscarriage rates	9 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026