Gas Embolism With Use of Argon Plasma Coagulation

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00676858

Enrollment

Registered

2008-05-13

Start date

2008-07-31

Completion date

2011-07-05

Last updated

2017-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Embolism, Air

Keywords

Embolism, Argon

Brief summary

The purpose of this study is to use transesophageal echocardiography (TEE) to determine the incidence, severity, and clinical significance of gas bubbles during argon plasma coagulation (APC).

Detailed description

Gas embolism is a rare but serious complication of APC. We will use TEE to monitor for gas bubbles during APC. APC will be terminated if gas bubbles are associated with ischemic heart rhythms, wall motion abnormalities, or if large gas bubbles are noted in the left ventricle.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults (male and female) 18 years of age or older * Clinical indication for bronchoscopy (hemoptysis, airway obstruction, tumor excision, granulation tissue that is impairing endobronchial stent performance) * Ability of the patient or proxy to read, comprehend, and sign informed consent document.

Exclusion criteria

* Presence of esophageal disorders that may complicate transesophageal echocardiography (strictures, varices, fistula, prior esophageal surgery) * Presence of coagulopathy or other bleeding diathesis * Inability to tolerate brief periods of apnea * Presence of pulmonary vascular disease * Pregnant women will not be included in this study because the potential fetal hypoxemia is not an acceptable risk. * No exclusions will be made based on gender or race.

Design outcomes

Primary

Measure	Time frame
incidence of gas bubbles with use of APC	end of procedure

Countries

United States

Outcome results