Use of Amnion on Partial Thickness Burns

Project Title The Treatment of Partial Thickness Burns: Treated Amnion Versus Currently in Use Topical Medications

Status

Withdrawn

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00674999

Acronym

Amnion

Enrollment

Registered

2008-05-08

Start date

2005-06-30

Completion date

2008-09-30

Last updated

2012-11-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn

Keywords

Burn, Partial thickness burn

Brief summary

To determine if Amnion, used on partial thickness burn injuries would provide an improvement in rate of healing, pain control and scarring as compared to standard medical treatments.

Interventions

BIOLOGICALAmnion

Application of Amnion with processing procedures involving the use of trypsin-EDTA

DRUGPolysporin/Bacitracin/Mycostatin

Application of Prepared antibiotic ointment: Polysporin, Bacitracin and Mycostatin combined

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Partial thickness burn injury. * \>2% burn injury. * Ages 0-100 years.

Exclusion criteria

* Patients not expected to survive

Design outcomes

Primary

Measure	Time frame
Length of time to 95% healing of treated burn wounds	Assessment daily until 95 % healed

Secondary

Measure	Time frame
Length of hospital stay	Measured at hospital discharge
Incidence of infection	Measure daily until complete wound healing
Amount of daily pain until wound is healed with different treatments.	Daily until wound is completely healed.
Amount of scaring with different treatments	From injury to 2 years post burn

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026