Cataract
Conditions
Keywords
posterior capsule opacification, micro incision, sharp optic edge
Brief summary
Studies showed that a sharp posterior optic edge of an intraocular lens (IOL) inhibits migration of lens epithelial cells in between posterior capsule and optic of the IOL and therefore reduces the rate of posterior capsule opacification (PCO). In present time most IOLs implanted have a sharp posterior optic edge. Due to differences in IOL production different IOLs have different rates of PCO. Progression in cataract surgery technique allow phacoemulsification through micro-incisions. Therefore there is need for IOLs that can be implanted through incisions of about 2.5 mm. This study investigates the effect of two different hydrophobic acrylic IOLs with a sharp posterior optic edge on the rate of PCO after implantation through a micro-incision. The results will be compared intraindividually.
Detailed description
prospective, randomized, bilateral study with intraindividual comparison, implantation of a Polylens Y10 IOL in one eye and implantation of a Polylens Y30 in the contralateral eye. PCO rate will be detected at 1 year and 2 years.
Interventions
PROCEDUREcataract surgery
cataract surgery with implantation of an IOL
Sponsors
Hospital Hietzing
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
55 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* bilateral age-related cataract * age 55 to 80 years * expected postoperative visual acuity of at least 0.5
Exclusion criteria
* amblyopia * corneal scars * diabetes * pseudoexfoliation-syndrome * earlier ocular surgeries or laser treatments * intraocular tumors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PCO rate | 2 years after surgery |
Countries
Austria
Outcome results
None listed